AMX0035 Prolonged Time to Ventilation, Tracheostomy in CENTAUR Trial
Treatment with AMX0035 significantly prolonged the time that people with amyotrophic lateral sclerosis (ALS) in the CENTAUR clinical…
Articles by Marisa Wexler, MS
Team Gleason, Synchron Unite to Advance Stentrode Device for ALS
Team Gleason and Synchron have entered into a partnership aiming to advance a technology that offers greater accessibility…
Lead Antibody Targeting Toxic TDP-43 Protein to Advance, ProMIS Says
ProMIS Neurosciences announced plans to advance a monoclonal antibody against toxic TDP-43 protein clumps as a potential treatment for amyotrophic lateral…
AMX0035 Extended Patients’ Survival By More Than 10 Months
Treatment with AMX0035 significantly extended the median survival of amyotrophic lateral sclerosis (ALS) patients by more than 10 months compared…
Wave Life’s WVE-004 Shows Proof of Concept in Cell, Mouse Models
WVE-004, Wave Life Sciences‘ experimental therapy for people with amyotrophic lateral sclerosis (ALS)Â associated with mutations in the C9ORF72…
Treg Therapy ALS001 Found to Ease Oxidative Stress in Early Trial
Treatment with Coya Therapeutics‘ ALS001, a regulatory T-cell (Treg) therapy being developed for amyotrophic lateral sclerosis (ALS), was found…
#AAN2022 – Biological Clustering May Help ID Fast-progressing ALS
“Clustering” people with amyotrophic lateral sclerosis (ALS) based on biological data could be useful for identifying those most likely…
WVE-004 Reduces Toxic Proteins, Early FOCUS-C9 Data Suggests
The experimental therapy WVE-004 appears to be engaging its intended target and reducing the amount of toxic proteins in people…
RNA-targeting CRISPR System Shows Promise in Preclinical Models
A CRISPR-based gene editing system could be used to reduce the activity of genes associated with amyotrophic lateral sclerosis…
Brain Implant Allows Paralyzed ALS Patient to ‘Speak’ With Family Again
A novel system that involves electrodes implanted in the brain allowed a 34-year-old man with amyotrophic lateral sclerosis (ALS)…