Masitinib, Given Early in ALS Course, Extends Life, Trial Data Show
Treatment with the investigational oral therapy masitinib can extend lifespan when given early in the course of amyotrophic…
Articles by Marisa Wexler, MS
Childhood Form of ALS Identified, Linked to SPLTC1 Mutations
A previously unknown form of amyotrophic lateral sclerosis (ALS) — one with onset during childhood — is caused by mutations…
Nearly $12M Grant Will Fund ALS Cell Therapy Trial at Cedars-Sinai
Cedars-Sinai Medical Center, in California, has been awarded an $11.99 million grant to support a clinical trial that will test…
Rare 2030 Action Campaign Pushing for European Plan for Rare Diseases
Eurordis opened a campaign, called Rare 2030 Action, that is seeking to establish a European action plan for…
MediciNova Secures European Patent for MN-166 Plus Riluzole
The European Patent Office will grant MediciNova a patent that covers the combination of MN-166 (ibudilast) and riluzole…
#AANAM – Trial Will Evaluate Tofersen in Presymptomatic SOD1 Patients
Editor’s note: The ALS News Today team is providing in-depth coverage of the 2021 Virtual AAN Annual Meeting, April 17–22.
3D Imaging System May Have Applications in ALS Research
A novel system for three-dimensional (3D) imaging of zebrafish may be useful for studying the motor and neuronal deficits linked…
Stretchable Electronics May Allow Wearable Sensors to Diagnose ALS
Stretchable electronics that are “intrinsically” stretchable — meaning they have tissue-like mechanical properties that integrate sensory devices with human skin…
Imaging Technique Measures Mitochondrial Abnormalities in ALS
An imaging technique, called 31-phosphorus magnetic resonance spectroscopy (MRS), can be used to assess mitochondrial abnormalities in people with…
TDP-43 Protein Abnormalities in ALS Linked to DNA Damage
Abnormalities in the activity of the protein TDP-43, whose gene is often mutated in amyotrophic lateral sclerosis (ALS), can…