Author Archives: Patricia Inacio PhD

Cell Metabolite Reduces Neuronal Death in ALS, Study Shows

In a new study entitled “Neuronal death induced by misfiled prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment,” researchers report that in protein misfolding neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Amyotrophic Lateral Sclerosis, neuronal death…

ALS Patients Improve with NurOwn™ Stem Cell Therapy, Study Shows

BrainStorm Cell Therapeutics, Inc., a biotechnology company focused on developing innovative, autologous stem cell therapies for highly debilitating neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS), recently announced the latest Phase 2a clinical trial results of NurOwn™, a technology that differentiates bone marrow-derived mesenchymal…

Disease Progression in ALS Linked To Increased Protein Instability

A new study entitled “Aggregation propensities of Superoxide Dismutase G93 hotspot mutants mirror Amyotrophic Lateral Sclerosis clinical phenotypes” identified a mechanism that leads to the aggregation of SOD protein mutant forms that are typically found in Amyotrophic lateral sclerosis (ALS) motor neurons. The study opens new therapeutic avenues…

ALS Risk Lowered Through Use of ACE-inhibitors, According To Study

A new study entitled “Angiotensin-Converting Enzyme Inhibitors and Amyotrophic Lateral Sclerosis Risk A Total Population–Based Case-Control Study” reports that using angiotensin-converting enzyme inhibitors (ACEIs) significantly decreases the risk for developing amyotrophic lateral sclerosis. The study was published in the journal Jama Neurology. Amyotrophic lateral sclerosis (ALS), also…