SIRION Biotech, Denali Therapeutics to Develop New AAV Vectors to Help Treat ALS
SIRION Biotech and Denali Therapeutics have signed a new licensing agreement to develop a new generation of adeno-associated…
Articles by Patricia Inácio, PhD
MIROCALS Webinar Will Discuss Novel Approach to ALS Trial Development
An upcoming webinar will focus on the novel approach to clinical trial design in the Modifying Immune Response and Outcomes…
Ibudilast-Rilutek Therapy Combo Closer to U.S. Patent for ALS and Other Neurodegenerative Diseases
MediciNova’s investigational therapy ibudilast (MN-166) combined with Rilutek (riluzole), for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, has been given…
Rescuing Levels of STMN2 May Be Potential New Therapy For ALS, Harvard Study Suggests
Harvard neuroscientists have discovered how the TDP-43 protein — previously linked to sporadic and inherited amyotrophic lateral sclerosis (ALS) cases —…
Early and Consistent Weight Loss Linked to Poorer Outcomes in ALS, Study Suggests
The rate of weight loss from onset to diagnosis can be a significant indicator of poorer outcomes among amyotrophic…
Axon-seq Lets Researchers Better Analyze mRNAs in Study of ALS
A new method called Axon-seq allows researchers to analyze the content of messenger RNAs (mRNAs) in the motor neuron’s axons,…
New Small Molecule Targets Root Cause of ALS and Frontotemporal Dementia, Study Reports
Researchers have developed a new small molecule that targets the most common genetic defect behind amyotrophic lateral sclerosis (ALS) and…
Cannabis Mouth Spray Sativex May Help Reduce Spasticity in ALS Patients, Phase 2 Trial Shows
Sativex, a mixture of two active compounds of cannabis, may help control symptoms of spasticity (stiff muscles) in people…
$2.5M Awarded to Investigate Mechanisms Linking Neurodegenerative Diseases to Infections
A new research project that will investigate the seemingly unrelated mechanisms between neurodegenerative diseases and infections has been awarded $2.5…
Strategies to Cope with ALS Need to Address Depression and Anxiety Together, Study Says
Depression and anxiety in amyotrophic lateral sclerosis (ALS) patients, even at low levels, are linked and should be addressed together, a…