ALS Researchers Identify Loss of MHCI Protein as Key in Development of Disease
Researchers revealed that the loss of major histocompatibility complex I (MHCI) is a key step in the development of amyotrophic lateral…
Articles by Patricia Inácio, PhD
ALS Patients’ Motor Neurons Degenerate at Accelerated Rate With Specific Enzyme
Researchers discovered that a metalloproteinase specialized in the degradation of chondroitin sulfate proteoglycans, called ADAMTS-4, promotes neurodegeneration in a mouse…
Increased Risk of ALS Appears Linked to Physical Trauma at Early Age
Physical trauma at earlier ages appears associated with an increased risk of amyotrophic lateral sclerosis (ALS), according to a study titled “…
Perturbed Transport into Cellular Nucleus Linked to ALS
Three recent studies published in the journals Nature and Nature Neuroscience identified a mutation in…
Two New Studies Identify Disrupted Trafficking Inside Neurons as the Cause for Known ALS Mutation
Two new studies, one entitled “GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport” and another “…
ALS P56S-VAPB Mutation Suppresses Muscle Fiber Formation
In a recent study entitled “ALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells”…
Single Traumatic Brain Injury Not a Contributing Factor for ALS Onset
In a new study entitled “Acute traumatic brain injury does not exacerbate ALS in the SOD1 model”…
New study Unravels How Motor Neurons Control Muscle Movement
In a new study entitled “Neural population dynamics in human motor cortex during movements in people with…
Study Finds Link Between Type 2 Diabetes And Amyotrophic Lateral Sclerosis
In a recent study entitled “Diabetes Mellitus, Obesity, and Diagnosis of Amyotrophic Lateral Sclerosis – A Population-Based…
Vitamin D Dietary Restriction Has Detrimental Effects in ALS Mouse Models, Study Shows
In a new study entitled “Dietary Vitamin D3 Restriction Exacerbates Disease Pathophysiology in the Spinal Cord of…