#MDA2021 – WVE-004 Treats Causes of ALS Due to C9orf72 Mutations in Early Study
Editor’s note: The ALS News Today team is providing in-depth coverage of the 2021 MDA Virtual Clinical and Scientific Conference,…
Articles by Steve Bryson, PhD
Shrinkage in Cell Structures Occurs in Early Disease Stages
Changes to a critical structure within the cell nucleus of spinal nerve cells — the nucleolus — preceded…
Compound Reverses Motor Neuron Damage in ALS Mice
For the first time, a compound was able to restore the health of diseased upper motor neurons — nerve cells…
Common Gene Variants Not Found in Maltese ALS Patients
Maltese people with amyotrophic lateral sclerosis (ALS) do not exhibit mutations in the genes commonly…
$2.2M Grant Aims to Move M102, Potential ALS Therapy, Into Trials
Work into moving M102, an investigative treatment for amyotrophic lateral sclerosis…
Experimental Test Could Detect ALS Before Symptom Onset
A method that measures tiny amounts of aggregated TDP-43 protein in the cerebrospinal fluid may have the …
BREN-02, Potential Restorative ALS Therapy, Named Orphan Drug by FDA
BREN-02, a lab-made form of the human protein engrailed 1 (EN1), has…
Stentrode Device Allows Computer Control by ALS Patients With Partial Upper Limb Paralysis
The Stentrode, a minimally invasive, fully implanted wireless device that transmits signals from…
Specific Immune Cell, With Human Equivalent, Seen to Reverse Nerve Damage in Mice
A newly identified type of immune cell — a kind of immature neurophil or white blood cell…
Nerve Injury Progressing in Top-down Manner Evident in Bulbar ALS
Most people with bulbar onset amyotrophic lateral sclerosis (ALS) showed distinct signs of…