News

ALS Association Awards Over $1.95M to 5 Projects Advancing Research and Therapies

The ALS Association has announced the five winners of its Translational Research Advancing Therapy for ALS (TREAT ALS) grant awards, advancing research projects into improved treatments and, eventually, a cure for amyotrophic lateral sclerosis. There are two types of grants — TREAT ALS Drug Development Contract and ALS Association-Initiated — which total more…

Help Someone with ALS Have a Voice

“The ALS Assistive Technology Challenge, a joint initiative by The ALS Association and Prize4Life is offering a $400,000 prize for the development of flexible, accessible technology to help people with ALS communicate with ease. The challenge is open to academics, industry, start-ups and anyone who believes they can…

Abnormal Proteins Found in ALS and Like Diseases Are ‘Tagged’ to Form Clumps, Study Reports

Scripps Research Institute (TSRI) scientists have identified a new player in the ribosome-associated quality control complex that “tags” abnormal proteins, prompting them to aggregate and form clumps. This study, for a first time, shows that proteins can be marked for aggregation, and may constitute a new molecular pathway underlying neurodegenerative diseases such…

ALS Study Finds Higher Than Usual Levels of Axon ‘Repellent’ Protein in Patients’ Motor Cortex

Motor neurodegeneration in amyotrophic lateral sclerosis (ALS) can begin in axons at neuromuscular junctions and later spread to the cell body in the spinal cord, in a phenomenon known as the “dying back” hypothesis. Proteins involved in axonal regeneration may, for this reason, represent a potential therapeutic target in ALS. A research team from Germany found…