News

In ALS, Sensory Neurons Found to Be Affected Early

In a recent study published in the Journal of Comparative Neurology, researchers found that the same sensory neurons that keep a person from dropping a glass of water are implicated in amyotrophic lateral sclerosis (ALS), and because these  neurons are easier to study in the laboratory than motor neurons, they…

Amylyx’s ALS Drug to Enter a Clinical Trial in 2016

Amylyx Pharmaceuticals was recently awarded $600,000 from the ALS Finding a Cure Foundation and the Cure Alzheimer’s Fund, in addition to an estimated $1.3 million raised through private investors, to develop its lead drug candidate AMX0035 for the treatment of amyotrophic lateral sclerosis (ALS) in a clinical trial planned for…

New ALS Study of Ibudilast in Patients Set to Start

MediciNova, Inc. recently announced that the U.S. Food and Drug Administration (FDA) has approved the protocol of a novel clinical trial in patients with amyotrophic lateral sclerosis (ALS) to assess MN-166 (ibudilast) on a biomarker of ALS. The Phase 2a trial, titled “A Single-Center, Open-Label Biomarker Study to…

ALS Neuroscience Focus Turns to Promising RNA Research

This week the ALS Association, whose mission is to lead the fight to treat and cure ALS through global research and nationwide advocacy, has highlighted important research from the 2015 Annual Meeting of the Society For Neuroscience, an event that took place in Chicago, Oct. 17–21. This meeting is the premiere venue…

ALS, in Some Forms, May Be Caused by Activated Retrovirus

Some forms of amyotrophic lateral sclerosis (ALS) could actually be caused by an infectious virus, with scientists reporting that human endogenous retrovirus-K (HERV-K), normally dormant, has been found in an active form in the postmortem brain cells of certain individuals with ALS. Experiments using the active HERV-K in cells grown in…