Simplesa Expands ‘Deanna Protocol’ Diet Supplement Choices for ALS Patients

Margarida Azevedo, MSc avatar

by Margarida Azevedo, MSc |

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redox environment in familial ALS

Simplesa, a nutrition company established in 2013 after the amyotrophic lateral sclerosis (ALS) community showed its support for its metabolic supplement called the Deanna Protocol, or DP diet, has expanded the Deanna Protocol Bundle Pack choices for consumers.

The Deanna Protocol is an all-natural metabolic program developed by Dr. Vincent Tedone, a retired physician whose daughter, Deanna, has ALS. Indicated for both men and women, the DP diet is meant to improve the quality of life for people with ALS. Patients who consistently follow the diet have reported an improvement in energy production, reduction in muscle twitching and cramping, and improved coordination, balance, and limberness.

Three research studies in mice, supported by the nonprofit ALS group Winning the Fight, have shown that the DP diet delays progression of ALS and extends lifespan though a mechanism that involves elevated tricarboxylic acid (TCA) cycle intermediates. Two of the studies were published in scientific journals, PLOSone and FASEB.

One study, “Increased TCA cycle intermediates in response to diet with Deanna protocol in ALS mouse model (578.3),” published in FASEB, associated the diet with “greater mitochondrial ATP production” in the mice, which, the authors said, “might be the reason of improved motor function and slower progression of disease.” The other, published in PLOSone by the many of the same University of South Florida researchers, reported similar results.

The diet’s popularity has enabled Simplesa to lower the costs of the Deanna Protocol Bundle Packs and pass those savings on to consumers, Simplesa said in a press release. The company is now offering a wider spectrum of bundle choices at lower prices for ALS patients, ranging from “Core” and “Plus” to “Comprehensive.”

“Our goal is to make following the Deanna Protocol as simple and cost effective as possible, the one thing that has not changed is that you will still get the same quality products and service,” Steve Margolis, president of Simplesa, concluded in the release.

According to the PLOSone study, the diet’s main ingredient is arginine-alpha-ketoglutarate (AAKG), a supplement thought to increase nitric oxide production and aid in vasodilation.