A research team at Penn Medicine recently found that hypermethylation is able to inhibit the development of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) in a study titled, “C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence.” The results are published in the journal…
Researchers at Johns Hopkins University recently published in the journal PLOS ONE a novel resource to aid in studies focused on amyotrophic lateral sclerosis (ALS) pathogenesis and related drug development. The study is entitled “A Comprehensive Library of Familial Human Amyotrophic Lateral Sclerosis…
Results from a recent Phase I clinical trial in patients with Amyotrophic Lateral Sclerosis (ALS) showed a safe cell therapy approach that may allow for the treatment of larger pools of patients for later-phase ALS trials. The study is published in the Journal of Translational Medicine.
The ALS Association is inaugurating its new Nevada Chapter after the group joined 39 affiliates throughout the country to work in collaboration with the local community in order to support finding effective treatments and a cure for amyotrophic lateral sclerosis (ALS). The National Board of Trustees of the association recently praised…
In a new study entitled “Exome sequencing of case-unaffected-parents trios reveals recessive and de novo genetic variants in sporadic ALS,” researchers report to have identified rare genetic variants underlying sporadic cases of amyotrophic lateral sclerosis. The study was published in the journal Scientific…
A new study on amyotrophic lateral sclerosis (ALS) provided evidence that certain areas of gray matter (GM) are disproportionately and asymmetrically vulnerable to the pathology of ALS. The study entitled “Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis” was published on the…
Positive results are in for Neuralstem, Inc.‘s phase 2 clinical trial “Dose Escalation and Safety Study of Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis.” The trial, received by the FDA in 2012, treated…
Robert Bowser from Barrow Neurological Institute and Adriano Chio from the University of Turin, Italy were recently awarded with the 2015 Sheila Essey Award by the American Academy of Neurology and the Amytrophic Lateral Sclerosis (ALS) Association. This award recognizes scientists’ research and contributions toward the prevention, management and eventual cure of ALS. Both researchers will receive the award…
The Muscular Dystrophy Association (MDA) continues to enhance its research and healthcare services programs and has recently hired two new Scientific Program Officers: Amanda Haidet-Phillips and Laura Hagerty, both Ph.D. They will be reporting to Grace Pavlath, also Ph.D, who joined MDA in the past year to be the Scientific Program Director…
A clinical trial led by Dr. Marta Kaminska from the McGill University Health Center in Canada is currently recruiting participants to enroll in a study to assess the use of non-invasive home ventilation by patients with amyotrophic lateral sclerosis (ALS) using the iVAPS mode. The study is entitled…
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