ALS Severity, Likely Progression May Be Evident in 2 of Brain’s ‘Resting State’ Networks

Activity seen in two of the brain’s resting state networks in amyotrophic lateral sclerosis (ALS) patients may be a sign of more severe and rapidly progressing disease in a person. These networks, at work when a person is not focusing on a specific task, were investigated in the study, “Investigating Default Mode and…

An analysis of inflammatory marker levels in blood samples from amyotrophic lateral sclerosis (ALS) patients, improves patient categoration and may help design future ALS clinical trials, according to a new study. The study “Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis,” was published in the journal…

Target ALS Foundation, focused on finding new treatments for amyotrophic lateral sclerosis (ALS), has selected RUCDR Infinite Biologics as the biorepository for banking and distributing the foundation’s human stem cell lines to be used in industry and research. The privately funded non-profit institution, funds consortia-based collaborative projects that aim to decrease obstacles…

Researchers at the University of Occupational and Environmental Health in Japan, reviewed advances for using natural plant compounds to regulate autophagy, a process in the development of many neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, muscular atrophies, spinocerebellar ataxia 3, and amyotrophic lateral sclerosis (ALS). The review “Natural compounds preventing…

A group of women in their 60s decided to go full Monty to raise awareness for amyotrophic lateral sclerosis (ALS). The idea came from lifelong friends of Wendy Rauwerdink of Sheboygan, Wisconsin, who had diagnosed with the disease. Her friends became engaged in the fight, always wanting to do more.

Amyotrophic lateral sclerosis (ALS) is commonly referred to as Lou Gehrig’s disease. But who was Lou Gehrig and how did his life impact awareness about the disease? Henry Louis Gehrig was born in New York, June 19, 1903, at a time when very few people were aware of ALS,…

Researchers reviewed both current and emerging technical approaches that show the most promise in the detection of upper motor neuron (UMN) degeneration of ALS patients. By assessing and comparing the utility of cutting-edge imaging and electrophysiological approaches, researchers hope to identify biomarkers for UMN dysfunction that can serve as early diagnostics for…

“Die Trying”, this Friday’s episode of HBO’s edgy half-hour newsmagazine series VICE, is about ALS and hosted by the show’s Senior Associate Editor Angelina Fanous who is battling the disease. A preview trailer can be viewed at: https://als.vice.com/. Living with ALS, Egyptian-born Fanous is now focusing on…

Amyotrophic lateral sclerosis (ALS) is a disease that progressively shuts down your muscles by attacking certain cells in the brain and spinal cord needed to keep our muscles moving. Eventually, patients will lose their mobility, have trouble moving, walking, swallowing and even breathing. There is no known cure for ALS…

Researchers at the Karolinska Institute in Sweden and the University of Barcelona in Spain studied the contribution of cellular redox environment changes to the stability and integrity of SOD1, a protein implicated in the development and progression of familial amyotrophic lateral sclerosis (ALS). A key finding was that mutations in the…