MDA Engage: California event highlights community connection

PRC-Saltillo and Team Gleason are partnering to help people with amyotrophic lateral sclerosis (ALS) maintain communication and connections with family, friends, and their communities as the disease progresses. Under the collaboration, PRC-Saltillo will contribute its expertise in speech-generating technology and augmentative and alternative communication (AAC), while Team…

I asked our smart speaker to play music by the Lumineers while I got my husband, Todd, washed up and out of bed this morning. One of their songs, “Nobody Knows,” played, and it resonated with me and our ALS journey. “Nobody knows how to say goodbye/…

One of my ALS symptoms is weak legs and feet, which keeps me constantly struggling to prevent further decline. Lately, I’ve been obsessed with how far I walk. Not with my ability to walk — I’ve been focused on that ever since my diagnosis in 2010 — but…

Some people with amyotrophic lateral sclerosis (ALS) experience subtle signs of the disease, such as pain and motor problems, in the years before they are diagnosed. The findings add to growing evidence that ALS may have a prodromal phase, a period in which people start to experience biological changes…

People with amyotrophic lateral sclerosis (ALS) may share genetic roots with people who have other neurodegenerative conditions, including frontotemporal dementia (FTD), even when no family connection is known, a new study suggests. The findings highlight the genetic overlap across the ALS-FTD disease spectrum and suggest that conventional family histories may…

A pivotal Phase 2/3 clinical trial comparing the experimental oral therapy CB03-154 with a placebo in people with amyotrophic lateral sclerosis (ALS) has completed enrollment in China, developer Zhimeng Biopharma announced. China’s Center for Drug Evaluation (CDE) cleared the trial to begin last year. It…

We’ve had a mild fall on Michigan’s Keweenaw Peninsula with no snow or frost yet, though we often have both before November arrives. But even with our good weather, I’m steeling myself to face the coming winter. I drained my hoses and hung them on the garage wall. I picked…

President Donald Trump has signed into law legislation to renew the Accelerating Access to Critical Therapies (ACT) for amyotrophic lateral sclerosis (ALS), a federal program aimed at supporting ALS research and helping patients access promising experimental therapies. The original ACT for ALS was signed into law in 2021…

A wide range of potentially modifiable factors related to lifestyle, the environment, mental and physical health, and socioeconomic circumstances may be linked to the risk of developing amyotrophic lateral sclerosis (ALS), a study in China suggests. The researchers identified 45 factors significantly associated with ALS in an analysis of…