ALS Study Finds Gene Mutation’s Toxic Effects Might Be Countered by an Associated Protein

Aggregates of dipeptide repeat proteins produced by the mutant gene C9orf72 — the most common genetic cause of amyotrophic lateral sclerosis — are toxic to neurons through interactions with a protein intended to clear cells of defective proteins, scientists reported. The findings provide a very specific focus for future drug…

In this TEDx Talks video, meet Hiro Fujita at the TEDx Tokyo 2014, and find out more about his story with ALS. Learn more about ALS here: https://bit.ly/ALSNewsToday…

In this Guardian 2013 video, find out more about the story of a motor neurone disease sufferer calling for the right to die with dignity. Learn more about ALS here: https://bit.ly/ALSNewsToday…

In this Simplesa video, meet Tommy Mastrodicasa, awesome “Rock Star and ALS Fighter”. Learn more about ALS here: https://bit.ly/ALSNewsToday…

In this ALS Association video, watch “Dr. Lucie Bruijn, Chief Scientist of The ALS Association, give an overview of the exciting science presented at the 26th International Symposium on ALS/MND 2015 in Orlando, FL” Learn more about ALS here: https://bit.ly/ALSNewsToday…

The Motor Neurone Disease Association is raising awareness of motor neurone disease with their campaign #LastSummer. “Ailsa is living with MND and wanted to share her story with you, since her diagnosis.” Learn more about ALS here: https://bit.ly/ALSNewsToday…

Mutations in the C9orf72 gene are the most common genetic cause leading to amyotrophic lateral sclerosis (ALS). Despite this, researchers have not been able to determine what the normal function of the gene really is. Now, scientists from Cedars-Sinai Medical Center in Los Angeles have revealed that the gene contributes to…

ALS can be very difficult to diagnose since there isn’t a specific procedure or test to ultimately establish the ALS diagnosis. It is only through several diagnostic tests (often used to rule out other diseases that mimic ALS) and a thorough clinical examination that a diagnosis can be established. According to the…

Kevin Swan was diagnosed with ALS in February of 2012. Within a couple of months of diagnosis, he left his job as Director of Communications for SingleHop, a rapidly growing infrastructure service provider, and founded A Life Story Foundation. A 501(c)(3) organization, ALSF’s mission is to tell the stories…

Eisai announced it has withdrawn its new drug application for an ultra-high dose Mecobalamin as a treatment for amyotrophic lateral sclerosis (ALS) in Japan, and is reviewing its next steps in consultation with Japanese regulatory officials. Mecobalamin is one of the co-enzyme forms of vitamin B12. As it is physiologically equivalent…