In a recent study entitled “ALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells” researchers investigated the role of a mutation associated with ALS type-8 (ALS8) – P56S-VAPB mutation – on skeletal muscle cells homeostasis and muscle formation. The study was published in the…
ALS P56S-VAPB Mutation Suppresses Muscle Fiber Formation
People who participated in last year’s Ice Bucket Challenge have helped to make a difference in the lives of ALS patients that live in the area of St. Louis. The ALS Association was able to double their donations, which increased the associations’ support for ALS patient care, education,…
A study led by researchers at the National Institute of Neurological Disorders and Stroke (NINDS) recently published in the journal Neuron revealed new insights into why mutations in the SOD1 gene lead to the development of amyotrophic lateral sclerosis (ALS). The study is entitled “…
A research team at Colombia University led by Lars Brichta and Paul Greengard identified two proteins responsible for neuronal cell loss in Parkinson’s disease (PD). The study entitled “Identification of neurodegenerative factors using translatome–regulatory network analysis” appeared on 27 July, 2015 in the journal…
The ALS Therapy Development Institute has just signed a research partnership with Chaperone Therapeutics, Inc., a company that specializes in treatments that address protein misfolding and neuronal cell loss, the underlying causes of neurodegenerative disease. The new partners will be working on potential treatments for amyotrophic lateral sclerosis (ALS), in order to facilitate preclinical development…
Researchers at the University of Massachusetts Medical School in the United States and the Babraham Institute in the United Kingdom recently revealed a new fly model to study motor neuron degeneration. The study was published in the journal Current Biology and is entitled “…
One of the country’s most accomplished professors of neurosurgery, neural and behavioral sciences and pediatrics at Penn State College of Medicine, James Connor, has just received a three-year grant worth $240,000 from the ALS Society to support his work on a nutrition-based solution that can be given via pain-medication delivery…
In a recent study published in Neurology, Neurosurgery & Psychiatry, a team of researchers found that men working as funeral directors may be at an increased risk for amyotrophic lateral sclerosis. According to the authors this might be related to the high probability of exposure to…
This month, the disease awareness campaign that took the internet and Hollywood by storm is making a comeback. Thanks to the renewed joint efforts of co-founders Pete Frates, Pat Quinn and Anthony Senerchia, a number of celebrities, the Boston Red Sox and Major League Basketball (MLB), the viral ALS Ice…
It has already been a year since the ALS Ice Bucket Challenge took the internet by storm, causing countless American households, celebrities and public figures to show support for ongoing efforts to find a cure for amyotrophic lateral sclerosis. In the wake of the viral campaign, a team of scientists…
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