The ALS Society of Canada and Brain Canada are supporting four early-career scientists who are working to advance an understanding of amyotrophic lateral sclerosis (ALS) and treatments for people with the disease. Grants totaling CA$390,000 (about $290,000) will fund projects by three doctoral students and one postdoctoral…

I remember the times before ALS, when after a day away from the house at work or running errands, I’d drive home in anticipation of seeing my late husband Jeff’s blue pickup truck in the driveway. Jeff and I would often arrive home at about the same time each…

An ongoing Phase 3 clinical trial in Europe is testing whether tauroursodeoxycholic acid, added to standard therapy, can slow disease progression and extend survival among people with amyotrophic lateral sclerosis (ALS). The oral compound, also known as TUDCA, is one of the two ingredients in Relyvrio (sodium phenylbutyrate…

People who took part in clinical testing of NurOwn, a cell therapy for amyotrophic lateral sclerosis (ALS), and family members have sent a letter in support of Brainstorm Cell Therapeutics and its investigational therapy to the U.S. Food and Drug Administration (FDA). They are also asking for an…

Shortly after I was diagnosed with ALS, I began to notice my reflexes acting kind of wonky. Pre-ALS, thanks to years of practicing yoga and tai chi, I considered myself a relatively calm and relaxed person. But now, any sudden loud noise or unexpected tap on my shoulder had…

The ALS Association and Paralyzed Veterans of America (PVA) are pressing the Congress to pass legislation boosting the financial support given the spouses and dependents of U.S. veterans whose death comes after nearly a decade of living with amyotrophic lateral sclerosis (ALS) due to their service. Specifically, the…

FundaMental Pharma, a spin-out preclinical neuroscience company from Heidelberg University, in Germany, has just been launched with €10 million in startup seed funding and a goal of developing new treatments for amyotrophic lateral sclerosis (ALS) and other diseases, according to a company…

An international team of researchers discovered how, during development, motor neurons — the nerve cells controlling movement whose death causes amyotrophic lateral sclerosis (ALS) — direct blood vessel growth around them while growing toward target muscles. Specifically, motor neurons were found to secrete a combination of signaling molecules that…

For most people, the holidays are a time of joy and good cheer, and an opportunity to get together with family and friends. But when living with ALS, social gatherings have the potential to add stress to an otherwise happy season. For anyone like me who has ALS-related…

ET-101, Eikonoklastes Therapeutics’ experimental gene therapy for amyotrophic lateral sclerosis (ALS), has been designated an orphan drug by the U.S. Food and Drug Administration (FDA). Orphan drug status is given to investigational therapies with the potential to significantly benefit people with life-threatening or chronically debilitating diseases that affect…