Showing 2682 results for "amyotrophic lateral sclerosis (ALS)"

Prilenia partners with Ferrer to advance pridopidine for ALS

Prilenia Therapeutics has entered a collaboration and license agreement with Ferrer to codevelop and commercialize pridopidine, its therapy candidate for neurodegenerative diseases like amyotrophic lateral sclerosis (ALS), in Europe and other select markets. The partnership comes as pridopidine nears an expected regulatory decision in the European Union, where…

Groups ask lawmakers to preserve National ALS Registry funding

ALS groups are asking lawmakers to preserve federal funding for the National ALS Registry and National ALS Biorepository, the first and only comprehensive nationwide resource to collect and analyze data for better understanding amyotrophic lateral sclerosis (ALS). “A recently leaked draft memo from the U.S. Department of Health and…

Aim this ALS Awareness Month is to amplify community voices

Across the U.S. and around the world, the amyotrophic lateral sclerosis (ALS) community is aiming to raise its voice in powerful ways this May during awareness month  — with advocacy campaigns, flag displays, the sharing of personal stories, and community-led events. ALS Awareness Month, according to supporters of those…

Brain-computer interface to restore speech named award winner

A neurosurgeon and his team from the University of California (UC) Davis Health have won The Herbert Pardes Clinical Research Excellence Award — given by the nonprofit Clinical Research Forum — for their work on a brain-computer interface that translates brain signals into speech with greater than 95% accuracy.

Treatment with Tregs safe, may slow ALS progression: Trial

Treatment with regulatory T-cells, or Tregs — a type of anti-inflammatory immune cell — was well tolerated and seemed to slow disease progression in a small clinical trial that enrolled six people with amyotrophic lateral sclerosis (ALS). The work was conducted by scientists at Columbia University in New…

FDA clears cell therapy XS-228 for ALS Phase 1 clinical trial

The U.S. Food and Drug Administration (FDA) has given Xellsmart Biopharmaceutical the go-ahead to start a Phase 1 clinical trial testing its stem cell-based therapy XS-228 in people with amyotrophic lateral sclerosis (ALS). This milestone, reflecting the approval of Xellsmart’s investigational new drug (IND) application, follows promising results…

3-drug combo shows promise for treating SOD1-ALS: Mouse study

A combination of three drugs — one of them the experimental therapy CuATSM — may be effective for treating amyotrophic lateral sclerosis (ALS) caused by mutations in the SOD1 gene, according to a new preclinical study. In mice carrying SOD1 mutations, the combination of these three drugs — CuATSM,…