Amyotrophic lateral sclerosis (ALS) patients with impaired swallowing show loss of taste perception, according to a new study. This problem is greater in patients requiring a feeding tube. The findings also suggested that using a device reproducing original food flavor may improve the patients’ quality of life. The study,…
A new research project that will investigate the seemingly unrelated mechanisms between neurodegenerative diseases and infections has been awarded $2.5 million from the Chan Zuckerberg Initiative (CZI). The funding was awarded to Ivan Marazzi, PhD, assistant professor of microbiology at the Icahn School of Medicine at Mount Sinai in New…
Graphene, a material made up of a thin sheet of carbon, may be used in the future to detect and measure biomarkers able to identify patients with amyotrophic lateral sclerosis (ALS), according to data from a recent study. The study, “Quantum Capacitance Based Amplified Graphene Phononics for Studying…
Global asset management company Affiliated Managers Group (AMG) has announced a $20 million matching gift to establish the Healey Center at Massachusetts General Hospital, the goal of which is to accelerate the development of amyotrophic lateral sclerosis (ALS) treatments. With this gift, which will fund over time,…
Depression and anxiety in amyotrophic lateral sclerosis (ALS) patients, even at low levels, are linked and should be addressed together, a study reports. Moreover, according to the study, support to caregivers is essential as the patient-caregiver relationship is of key importance in coping with ALS. The study, “Death…
Anelixis Therapeutics has begun dosing patients in the first human trial of its amyotrophic lateral sclerosis (ALS) treatment candidate, AT-1501, the company announced. The trial is currently enrolling both healthy volunteers and eight ALS patients to test AT-1501’s safety and tolerability. Researchers will also examine how the agent behaves…
An experimental gene therapy based on RNA interference (RNAi) shows potential to treat patients with familial amyotrophic lateral sclerosis (ALS) caused by mutations in the superoxide dismutase 1 (SOD1) gene, according to results of a preclinical study in nonhuman primates. The study, “Safe and effective superoxide…
The amount of time it takes to diagnose amyotrophic lateral sclerosis (ALS) and the use of Rilutek (riluzole) to treat it vary significantly across Canada, according to a new nationwide analysis of a patient registry. These findings highlight the need for future studies to identify the factors that contribute…
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a disease that progressively destroys the nervous system. Over time, the nerve cells in the brain and spinal cord die and patients lose the ability to perform daily tasks, such as dressing, feeding, and moving. ALS is caused…
Mexiletine is a treatment approved by the U.S. Food and Drug Administration (FDA) to treat irregular heartbeat. It may also be used to treat muscle cramps in amyotrophic lateral sclerosis (ALS). How mexiletine works ALS is a serious condition characterized by the progressive loss of motor neurons…
