The U.S. Federal Trade Commission (FTC) sent warning letters to three companies that sell cannabis-based products containing cannabidiol (CBD), cautioning them that making unsubstantiated claims about the health benefits of CBD could lead to legal action. The agency “urges the companies to review all claims made for…

The benefits of riluzole, an approved treatment for amyotrophic lateral sclerosis (ALS), is thought to partly lie in its antioxidant effects. A new study now reports that this activity can be enhanced by combining it with agents like Radicava that provide protection via different pathways. The study, “…

Daily use of levosimendan capsules appear to preserve respiratory strength in people with amyotrophic lateral sclerosis (ALS) while in a supine, or lying flat, position, a sub-analysis of the Phase 2 LEVALS trial reports. Treatment did not show significant benefit against placebo when patients were sitting up, its primary…

Assessing the degree of atrophy, or shinkage, in facial nerves with a high-resolution imaging tool appears to provide an accurate and early diagnosis of amyotrophic lateral sclerosis (ALS), according to new research. The study, “Facial nerve atrophy in patients with amyotrophic lateral sclerosis: Evaluation with fast…

Inhibition of a protein called Cdk5 in the brain increases lifespan and improves motor function in mice with amyotrophic lateral sclerosis (ALS), a new study reports. This evidence supports a potential role for Cdk5 in the progression of ALS and opens new avenues as a potential therapeutic target for…

A new molecular mechanism that contributes to the death of some nerve cells has been discovered by a team of scientists led by researchers at Oregon State University. The researchers found that blocking a protein called HSP90 can result in the activation of a receptor present in motor…

Mutations in the FUS gene, one of the most common causes of familial amyotrophic lateral sclerosis (ALS), increase the number of branches extending from the axons of motor nerve cells, so that no clear path exists for these neuronal “arms” to transmit information — in the form of electrical impulses —…

People with amyotrophic lateral sclerosis (ALS) have higher blood serum levels of neurofilament light chain (sNfL) than do healthy people, a new study found. Its work also further supported sNfL’s usefulness as a marker of likely disease progression and outcomes, with higher concentrations indicating poorer survival. The research, “…

Excessive energy demands to overcome gravity in nerve cells directed downward — such as those involved in the control of limb movements — may explain why amyotrophic lateral sclerosis (ALS) affects certain motor neurons while leaving others untouched, a study has proposed. As people age, nerve fibers disposed vertically…

Disarm Therapeutics has announced the publication of two studies that further researchers’ understanding of the structure and function of SARM1, a key protein in cellular degeneration. The new data may aid in the design of therapies for multiple diseases, including amyotrophic lateral sclerosis (ALS). The findings were published in…