A clinical trial led by Dr. Marta Kaminska from the McGill University Health Center in Canada is currently recruiting participants to enroll in a study to assess the use of non-invasive home ventilation by patients with amyotrophic lateral sclerosis (ALS) using the iVAPS mode. The study is entitled…

In this video by NathanAndRose, watch Rose describe the amyotrophic lateral sclerosis disorder (ALS) and the American organization (ALS Association) which is searching for the cure. Learn more about ALS here: https://bit.ly/ALSNewsToday…

The U.S. Food and Drug Administration (FDA) has approved Tiglutik, an oral suspension of riluzole, for the treatment of amyotrophic lateral sclerosis (ALS). Rilutek (riluzole, by Sanofi) has been available in the U.S. as 50 mg tablets since December 1995. However, ALS patients can have difficulties with…

Combining two blood biomarkers may make the diagnosis of amyotrophic lateral sclerosis (ALS) more accurate and help predict how fast the disease will progress, according to a new German study. The two markers are soluble neurofilament light chain, called sNfL — a known marker of nerve damage — and…

In a new study entitled “Neuronal death induced by misfiled prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment,” researchers report that in protein misfolding neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Amyotrophic Lateral Sclerosis, neuronal death…

A study found that genetic mutations associated with amyotrophic lateral sclerosis (ALS) lead to problems with the function and transport of mitochondria, cellular structures needed for energy production, early in the disease course, before abnormal protein clumps are formed. “We show that the nerve cells, termed motor neurons, that…

According to a July 2014 report in the Morbidity and Mortality Weekly Report (MMWR), amytrophic lateral sclerosis (ALS) or Lou Gehrig’s disease is estimated to affect about 3.9 individuals for every 100,000 Americans, most commonly diagnosed in the elderly who are in their 70s. While…

Investigators at the Northwestern University Feinberg School of Medicine are currently enrolling participants for a clinical trial (ClinicalTrials.gov Identifier: NCT00821132), that aims to identify genes that increase risk for sporadic Amyotrophic Lateral Sclerosis (ALS) or cause inherited ALS. The study, entitled “Identification of Genes Causing Familial ALS or Increasing Risk…

In this video from Philly Philms, watch how the evolution of technological devices are now providing a way for people with low mobility in their upper-body to be able to communicate with other people with the help of assistive technology. Amyotrophic lateral sclerosis (ALS)…

A growth factor called FGF4 can reduce the activity of astrocytes — star-shaped cells in the brain and spinal cord that become overly reactive in amyotrophic lateral sclerosis (ALS) — but it doesn’t stop motor neurons from dying, a study in cells and mice found. The researchers also observed…