Cytokinetics has enrolled the first patient in the VIGOR-ALS extension trial (NCT02936635), which will assess the effects of tirasemtiv in patients with amyotrophic lateral sclerosis (ALS) who participated in the Phase 3 VITALITY-ALS (NCT02496767) study. Tirasemtiv is a novel skeletal muscle activator that triggers the muscle troponin complex, increasing…
The Les Turner ALS Foundation had about 7,000 people on more than 200 teams support those affected by amyotrophic lateral sclerosis (ALS) at the Les Turner ALS Walk for Life, held Sept. 18 in Chicago. The Les Turner ALS Foundation was founded in 1977 to support research, patient care, and education about…
The U.S. Food and Drug Administration (FDA) has designated  MediciNova’s Ibudilast (MN-166) an orphan drug as a potential treatment for amyotrophic lateral sclerosis (ALS). Ibudilast is a first-in-class, orally bioavailable small molecule phosphodiesterase (PDE)-4 and -10 inhibitor and a macrophage migration inhibitory factor (MIF) inhibitor that suppresses pro-inflammatory cytokines and promotes neurotrophic factors.
In this Houston Methodist video, we get to meet Kevin Kinchen. Kevin was diagnosed with amyotrophic lateral sclerosis (ALS) six years ago, but he hasn’t let that stop him from getting on with his life. Nanci is a much-loved Hollywood publicist who was diagnosed with amyotrophic lateral sclerosis (ALS)…
Patients with amyotrophic lateral sclerosis (ALS) experience a gradual loss of the ability to walk, swallow and even breathe, and there’s no cure. It’s incredibly important that patients seek specialized treatment to address the different aspects of the disease. Find out seven ways to diagnose ALS. In this…
An analysis of previously published data suggests that neurofilaments in the blood and spinal fluid of people with amyotrophic lateral sclerosis (ALS) may be used to assess disease progression and neurodegeneration in general. Levels of the factor also were higher in ALS patients than in patients with diseases mimicking ALS,…
Augie’s Quest announced the 11th annual ‘Tradition of Hope’ gala event will be held Oct. 15 at the Beverly Hilton Hotel to raise funds for amyotrophic lateral sclerosis (ALS) research. Augie’s Quest is a cure-driven nonprofit effort dedicated to finding treatments and a cure for ALS. The effort…
AB Science has been invited to present new preclinical studies on masitinib in the treatment of amyotrophic lateral sclerosis (ALS) at four international meetings this year. These were the main findings from the series of preclinical studies: Proof of concept data from the preclinical trials of masitinib showed that the investigational drug “targets…
Find out more about the story of Nanci Ryder in this ALS Association video. Nanci is a much-loved Hollywood publicist who was diagnosed with amyotrophic lateral sclerosis (ALS) in 2014. Read about the four ALS heroes the ALS Association chose to honor for outstanding contributions. The ALS Association’s…
Amyotrophic lateral sclerosis (ALS) would benefit from a new classification system, according to a group of researchers who highlighted the shortcomings of current systems for diagnosing the disease and allocating patients to subtypes of the condition. The opinion article, “Amyotrophic lateral sclerosis: moving towards a new classification…
