Skip to content
ALS News Today logo Newsletter
Newsletter
  • About ALS
    What is ALS?
    Causes and risk factors
    Diagnosis
    Symptoms
    • Speech problems
    • Breathing and swallowing
    • Pseudobulbar affect
    Types of ALS
    • Familial ALS
    • Sporadic ALS
    Living with ALS
    • Mental health
    • Diet
    • Exercise
    • Aids and adaptations
  • Treatments
    Approved treatments
    Experimental treatments
    Non-drug treatments
  • News
  • Columns
    Joyful Sorrow — Kristin Neva
    Living Well With ALS — Dagmar Munn
    Thunder Road — Juliet Taylor
    Archived columns
    • OutSpoken — James Clingman
    • The Mighty Mind — Rachel Doboga
    In memoriam
    • Notes From the ALS Front — Rick Jobus
  • Forums
  • Advocacy partners
  • What can we help you find today?

June 4, 2019 News by Ana Pena, PhD

SOD1 Enzyme Clumps May Expose Cells to DNA Damage in Some ALS Patients, Study Suggests

The enzyme superoxide dismutase 1 (SOD1) forms clumps inside the cells of some people with sporadic amyotrophic lateral sclerosis (ALS), making them more vulnerable to DNA damage — which may contribute to the neurodegeneration that marks the disease, an early study suggests. In other patients, SOD1 is transported…

November 7, 2018 News by Patricia Inácio, PhD

FUS Mutation Common to Familial ALS Impacts DNA Repair Pathways in Motor Neurons, Study Shows

Mutations in a gene linked to familial amyotrophic lateral sclerosis (ALS), called FUS, affect the ability of motor nerve cells to repair damage to their DNA, a new study shows. These findings suggest that therapies that enhance the repair of DNA damage may be of benefit to some ALS patients.

October 1, 2018 News by Iqra Mumal, MSc

FUS Mutations Likely Cause ALS by Preventing Repair of Oxidative Damage in DNA

FUS  — a protein mutated in some amyotrophic lateral sclerosis patients  — plays a key role in the mechanism that repairs oxidative damage in DNA molecules in motor neurons, a study found. The findings suggest a mechanism through which FUS defects cause amyotrophic lateral sclerosis (ALS), and add to the…

Recent Posts

  • First Hoffman award winners to expand multidisciplinary ALS care
  • Access to investigational ALS therapy MN‑166 expanded further
  • AUT00201 boosts muscle strength, coordination in ALS mouse model
  • People with ALS should be able to proactively get feeding tubes
  • Zhimeng cleared to launch study of ALS therapy CB03-154 in China


Bionews, Inc.

3 W Garden St
Suite 700
Pensacola, FL 32502
Website: bionews.com
Email: info@bionews.com
Phone: 1-800-936-1363

  • About Us
  • Leadership
  • Our Culture
  • Editorial Policy
  • Advertising Policy
  • Corrections Policy
  • Terms of Service
  • Privacy Policy
  • Careers
  • Contact Us
Disclaimer

This site is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Copyright © 2013-2025 All rights reserved.