Flex Pharma Investigates FLX-787 as Treatment for Cramps in ALS Patients

Flex Pharma is launching the Phase 2 COMMEND trial, which will investigate the effects of FLX-787 in patients with muscle cramps associated with amyotrophic lateral sclerosis (ALS). The preliminary results of the trial are expected to be released in mid-2018. The COMMEND trial (NCT03196375) will start with an assessment…

ALS Study Shows Muscle Activators Might Reduce Cramping

Flex Pharma, Inc., a biotechnology company developing novel proprietary treatments for spasms and nocturnal and exercise muscle cramps associated with severe neuromuscular diseases, like amyotrophic lateral sclerosis (ALS) and motor neuron disease (MND), recently presented data demonstrating the role of efficacy of combinations of two molecules, TRPA1 and TRPV1 agonists, in reducing muscle cramp…