Ask Your Doctor if TIGLUTIK® (riluzole) is Right for You

TIGLUTIK is the only formulation of riluzole approved for both oral and PEG tube administration. It can be used throughout all stages of ALS. One dose of TIGLUTIK has the same amount of riluzole as RILUTEK 50 mg (riluzole tablets) and it is taken twice a day.

How Do You Take Your Medication?


TIGLUTIK is the only formulation of riluzole indicated for both oral and PEG tube administration. It is a suspension medication and is administered using the oral syringes supplied with the TIGLUTIK kit. Finally, people with ALS have a formulation of riluzole specifically designed to meet their needs, whether they have difficulty swallowing or have a PEG tube.

  • TIGLUTIK® (riluzole) Berwyn, PA: ITF Pharma; March 2020.
  • Rilutek (riluzole) Cary, NC: Covis Pharmaceuticals, Inc.; July 2016.
  • Data on file. ITF Pharma. Berwyn, PA; December 2019.

Important Safety Information

  • You should not take TIGLUTIK if you are allergic to any of its ingredients.
  • TIGLUTIK can cause liver injury, including death. Your doctor should do blood tests to check your liver function before and during your treatment and may stop treatment with TIGLUTIK if liver function is not normal. Contact your doctor immediately if you have unexplained nausea, vomiting, abdominal pain, fatigue, anorexia, or jaundice and/or dark urine.
  • Call your doctor immediately if you have a fever, cough, or difficulty in breathing while taking TIGLUTIK.
  • If you miss or skip a dose of TIGLUTIK, do not take any extra dose to make up for those you missed, but take your prescribed dose at the next regularly scheduled time.
  • The most common side effects of TIGLUTIK that occurred during medical studies were numbness/ tingling around the mouth, weakness, nausea, decreased lung function, high blood pressure, and abdominal pain. If any side effects become troublesome, contact your doctor.
  • Be sure to tell your doctor and pharmacist about all other health conditions you have and all medicines you are taking, including nonprescription products and vitamins. If you have questions, please talk to your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-332-1088.

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