FAQs about Tregs

Category: Tregs

Regulatory T-cells (Tregs) are part of the body’s immune system. Tregs are a type of white blood cell that works to suppress the immune response and limit excessive inflammation.

Category: Tregs

Research is ongoing to determine whether treatments based on regulatory T-cells (or Tregs) can help ease amyotrophic lateral sclerosis (ALS). Researchers want to see if boosting their levels and/or action in the early stages of ALS could slow disease progression.

Category: Tregs

A number of studies in people with amyotrophic lateral sclerosis (ALS) have shown it’s safe in a laboratory setting to collect and expand a patient’s own regulatory T-cells, boost their immunosuppressive action, and then infuse them back into that person. Although small in scale, such studies have shown the procedure is safe and well tolerated.

Category: Tregs

Research has made a link between decreasing regulatory T-cell (or Treg) levels in people with amyotrophic lateral sclerosis (ALS) and an increased rate of disease progression. Moreover, Tregs of ALS patients are known to become dysfunctional, with reduced anti-inflammatory and immunosuppressive actions, contributing to neuroinflammation and the disease symptoms.

Category: Tregs

Lifestyle factors such as military service, smoking, exposure to toxic chemicals, and strenuous exercise are risk factors for developing amyotrophic lateral sclerosis (ALS). Other possible risk factors include head trauma, electrical shock, and certain viral infections. Biological factors such as gender, age, and immune response also can contribute to developing the disease.