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ALS Outcomes Improve With Coordinated Healthcare

It makes sense that when healthcare providers work together, better outcomes can result for people with amyotrophic lateral sclerosis (ALS). A new study supports this idea by showing that coordinated networks of care for ALS can result in fewer trips to the hospital, less deterioration and an expanded lifespan. The study, titled…

A New Gene Called TBK1 May Contribute to ALS

Changes in a house-keeping gene that cleans up damaged proteins from cells may be in part to blame for Lou Gehrig’s disease, according to a study published online March 24 in Nature Neuroscience, titled “Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia.” Lou Gehrig’s…

Cognitive Impairment Comes Before Motor Degeneration in ALS, Study Shows

A research team led by Diego Minciacchi of the University of Florence in Italy identified a population of neurons that might explain the cognitive alterations antecedent to motor symptoms in Amyotrophic Lateral Sclerosis (ALS). The study entitled, “Increased anxiety-like behavior and selective learning impairments are concomitant to…

ALS Patients’ Health Decisions Rely on Multiple Factors

A study at King’s College London with patients recruited from the South-East ALS Register in England concluded that decision-making processes for ALS patients are complex, multidimensional and need individualized treatment and more patient-focused support. The results were presented in a publication entitled: “Accepting or…

New Experimental Model Uses Astrocytes to Test Therapies for ALS

A research team from the University of Wisconsin-Madison Waisman Center led by Su Chun Zhang, established a simple model in mice to investigate the role of human astrocytes in neurologic diseases such as Amyotrophic Lateral Sclerosis (ALS), Rett Syndrome and Huntington’s disease. The study entitled…

Genervon’s One-Patient ALS Drug Study Reveals Promising Results

Biopharmaceutical company Genervon recently reported observing improvements in a 46-year-old-man with advanced amyotrophic lateral sclerosis (ALS) taking the Company’s drug candidate GM604. The patient showed increased speech, swallowing and suction capabilities after a 12-week treatment. The drug, which has yet to be approved by the…

ALS Study Shows Benefits of NurOwn Stem Cell Therapy

New York and Israel-based, BrainStorm Cell Therapeutics, Inc., announced positive final results from a clinical trial of NurOwn™ in amyotrophic lateral sclerosis (ALS). The study reached its main goal, showing that NurOwn™ is safe and well-tolerated. In addition, the majority of the 14 participants in this study had an improvement (slowing)…