Protein Clusters Move Along Cells to Drive Immune Response, Study Suggests
Clusters containing a protein called LAT use specific adapters to move and drive the activation of T-cells to fight off…
Articles by José Lopes, PhD
Altered Gut Microbiota in ALS Patients Could Drive Digestive Problems, Study Suggests
People with amyotrophic lateral sclerosis (ALS) have an altered composition of their gut microbial community, with an increase in…
Cognitive Problems Have Limited Impact on Quality of Life in ALS, Study Suggests
Cognitive problems have limited impact on overall health-related quality of life (QoL) in people with amyotrophic lateral sclerosis…
FDA Places Hold on Approval Request for Nurtec, Sublingual Version of Riluzole
Concerns over an active pharmaceutical ingredient used in a 2017 study of Nurtec (riluzole) as a bioequivalent medicine were…
Prostate Gland Enlargement Does Not Increase ALS Risk, Study Reports
Men with benign prostatic hyperplasia (BPH) — prostate gland enlargement — are not at greater risk of amyotrophic…
Helping Motor Neurons in Spinal Cord Break Down Toxic Proteins as Well as Other Cells Do May Treat ALS, Study Finds
Differences in how efficiently nerve cells degrade and discard proteins may explain why some motor neurons better resist a buildup…
$8 Million Award Will Help Researchers Develop Early Warning Systems for ALS, Other Disorders
Scientist Manish Arora, PhD, received an $8 million Outstanding Investigator Award from the National Institute of Environmental Health…
Metabolic Changes Do Not Identify Who Will Develop ALS, Study Finds
Although people who develop amyotrophic lateral sclerosis (ALS) have altered levels of several blood metabolites — products of our…
#AANAM – Genetic Testing Useful for ALS Diagnosis, with Few Patient Concerns for Impact on Well-being, Studies Report
Only a minority of amyotrophic lateral sclerosis (ALS) patients are concerned about a possible negative impact of genetic testing…
#AANAM – Vitamin D Activator is Muscle Biomarker in ALS, May Indicate Clinical Progression, Study Contends
A vitamin D activator molecule known as CYP27B1 is a biomarker of muscle alterations in patients with amytrophic lateral…