Studying Epigenetic Changes Could Lead to New ALS Treatments and Biomarkers, Researchers Suggest
A specific type of genetic alteration — known as epigenetic changes — observed in patients with amyotrophic lateral sclerosis…
Articles by José Lopes, PhD
Transplanted Human Bone Marrow Cells Hold Promise as ALS Therapy, Mouse Study Shows
Transplanting certain human bone marrow cells into mice with amyotrophic lateral sclerosis (ALS) improved their motor function and preserved…
ALS Prevalence Higher Among Medicare Population, Study Finds
Amyotrophic lateral sclerosis (ALS) prevalence in a large group of patients with Medicare coverage was found to be higher…
Nerve-protecting Cells Hold Potential in Development of ALS Therapies
A specific type of supporting cells called Schwann cells protect against nerve degeneration induced by the blood-clotting protein thrombin, according…
Caregiver Burden Tied to Patients’ Level of Apathy in Study
Higher levels of apathy — particularly its behavioral symptoms — in people with amyotrophic lateral sclerosis (ALS) are associated…
Markers of Oxidative Stress, Other Factors May Predict Disability in ALS
Markers of oxidative stress, iron metabolism in the brain and nerve cell damage may accurately predict disability in patients with…
Exposure to Environmental Pollution Reduces Survival Rates of ALS Patients, Study Reports
Amyotrophic lateral sclerosis (ALS) patients with higher levels of organic pollutants in their blood have reduced survival rates, according…
Study Adds to Evidence that Smoking Increases Risk for ALS
Smoking is associated with a greater risk of developing amyotrophic lateral sclerosis (ALS), according to a new study. The…
ALS Patients, Caregivers Want to Know More About Genetic Testing, Survey Shows
Greater knowledge about clinical trials and the importance of genetic testing, as well as increased access to expert care,…
Experimental Gene Therapy Successfully Silences Key ALS Gene C9orf72, Preclinical Studies Show
A gene therapy candidate targeting a key amyotrophic lateral sclerosis (ALS) mutation in the C9orf72 gene is able…