Ventilation Support May Explain Why African American ALS Patients Live Longer
Rates of invasive assisted ventilation are 3.2 times higher in African Americans with amyotrophic lateral sclerosis (ALS) compared to Caucasian…
Articles by Patricia Inácio, PhD
Long-term Exposure to Mercury Linked to ALS in Older Patients, Case Report Suggests
Long-term mercury exposure over a period of years may increase the risk of amyotrophic lateral sclerosis later (ALS) in life,…
MRI Can Detect Difficult-to-Assess Muscle Damage in ALS, Small Study Reports
Magnetic resonance imaging (MRI) may help detect muscle damage in amyotrophic lateral sclerosis (ALS) patients, in particular muscles that are…
Young Researcher Awarded for Work on Processes Driving Development of ALS and Frontotemporal Dementia
Biochemist Dorothee Dormann, PhD, at the Ludwig Maximilians University, in Munich, was awarded the 2019 Paul Ehrlich and…
Occupational Exposure to Silica May Increase Risk of ALS, Study Suggests
Occupational exposure to silica is linked to a significantly increased risk of amyotrophic lateral sclerosis (ALS), a population-based study suggests.
Rescuing Impaired Skeletal Muscle Function May Help Relieve Some ALS Symptoms
Loss of normal ion flow in the skeletal muscle may worsen symptoms of amyotrophic lateral sclerosis (ALS), a mouse study…
ALS-linked Mutations Promote Accumulation of Brain Waste, Fruit Fly Study Shows
Loss of a protein known as ubiquilin causes defects in degradation centers called lysosomes, promoting the buildup of brain waste…
Gene Therapy Targeting SARM1 May Inhibit Neuron Degeneration in ALS, Mouse Study Shows
A gene therapy designed to block the activity of SARM1 protein prevented the loss of axons — long projections that connect…
Orion Launching Extension Study for ALS Patients Enrolled in Phase 3 REFALS Trial
Amyotrophic lateral sclerosis (ALS) patients who complete the ongoing Phase 3 REFALS clinical trial evaluating levosimendan (also known as ODM-109)…
Loss of Enzyme May Contribute to Motor Neuron Death in ALS, Study Shows
The loss of a key enzyme, called adenosine deaminase, in astrocytes — the energy-supporting cells of neurons — leads to…