The U.S. Department of Defense (DOD) has awarded a $1.475 million grant to Aclipse Therapeutics to advance M102 — an experimental oral therapy for amyotrophic lateral sclerosis (ALS) — into first-in-human clinical trials. The therapeutic development award comes from the Congressionally Directed Medical Research Programs (CDMRP) at the…
Aclipse Will Use $1.4M DOD Grant to Advance M102 to Clinical Trials
Note: Frontiers in Genetics, the publisher of the study discussed in this ALS News Today news story, received a request from the article’s authors to retract it in light of new information indicating that the variants reported in the study might not be meaningful; instead, they may actually result from…
The ALS Association is calling for applications for a new Seed Grant Program designed to support exploratory amyotrophic lateral sclerosis (ALS) research. The one-year grants of up to $50,000 each will fund investigations that could have a significant impact on the progressive neurodegenerative disorder. Specifically, funded projects…
Author and counselor Douglas C. Smith wrote in Health and Happiness U.P. Magazine about five types of grief people are experiencing through the pandemic. As I read through the article, I realized I have experienced all of them — anticipatory, general, disenfranchised, ambiguous, and vicarious grief — with my…
Shortly after Jeremy Schreiber, then 39, was diagnosed with amyotrophic lateral sclerosis (ALS), he had another life-altering decision to make. “I had a choice — climb into bed and pull the covers over my head or say ‘[expletive] it’ and fight this thing head-on,” Schreiber wrote in an excerpt…
“The secret of life is enjoying the passage of time.” Time fascinates me, now more than ever. In my own way, in the face of ALS, I’ve learned to enjoy its passing. I am writing this seconds after hearing…
Occupational exposure to lead — a heavy metal — prior to disease onset is associated with a more severe disease progression and lower survival among people with amyotrophic lateral sclerosis (ALS), according to a recent study. “In survival analysis of an international cohort [group] of ALS cases, our results…
The Canadian province of British Columbia is giving another CA$2 million (about $1.65 million) to help establish “Project Hope” — what organizers hope will be a world-class amyotrophic lateral sclerosis (ALS) center at the University of British Columbia (UBC). With the new funding, to the ALS Society…
I’m always eager to help others improve their understanding of what it’s like to live with amyotrophic lateral sclerosis (ALS). Likewise, I enjoy learning more about what others in the ALS community think and feel about living with the condition. Recently, I had the opportunity to satisfy both interests and…
The Jane Calmes ALS Scholarship Fund wants to help support students who wish to pursue undergraduate studies, but whose families have been impacted financially by amyotrophic lateral sclerosis (ALS). This is the fourth year The ALS Association, together with Mark Calmes, is offering support to U.S. post-high…
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