“It’s hard to make predictions … especially about the future.” –Yogi Berra Gamblers and non-gaming speculators fervently seek out “sure things.” In the absence of that, both groups attempt to identify situations where probability weighs heavily in their favor. Some may conspire to unscrupulously influence the odds in…
How a Friend’s Strength Taught Me to Cope With ALS
Widely used to study several human diseases, zebrafish can now be a useful preclinical model to study amyotrophic lateral sclerosis (ALS) linked to angiogenin mutations, according to researchers at the University of Bath. The model was described in a study, “…
Like many others in my ALS community, I try to keep up with ALS-related news and research. I’ll admit, though, that reading some scientific terminology makes my eyes glaze over. However, I do have a few favorite topics, including exercise, quality of life, and emotional well-being. Recently,…
Long-term mercury exposure over a period of years may increase the risk of amyotrophic lateral sclerosis later (ALS) in life, a case report suggests. The study, “Heavy metal intoxication and amyotrophic lateral sclerosis: causal or casual relationship?” was published in the journal Aging Clinical and Experimental Research.
Magnetic resonance imaging (MRI) may help detect muscle damage in amyotrophic lateral sclerosis (ALS) patients, in particular muscles that are difficult to access using standard techniques, a small study finds. The research was published in an article, titled “A pilot study assessing T1-weighted muscle MRI in amyotrophic lateral sclerosis,”…
A model of motor neuron disease based on patient-derived stem cells won the 2018 International 3Rs Prize for its potential to lessen or replace the use of animals as models in amyotrophic lateral sclerosis (ALS) research. The prize, given by the National Center for the 3Rs (NC3Rs) and sponsored by …
Amylyx has completed patient recruitment for the Phase 2 clinical trial CENTAUR, which addresses the safety and effectiveness of AMX0035 as an oral treatment for amyotrophic lateral sclerosis (ALS). In 2017, Amylyx launched…
“I think, therefore I am.” I have long been fascinated by that argument of philosopher Rene Descartes. Similarly, over a millennium earlier, St. Augustine wrote, “I make mistakes, therefore I am.” Both suggest that cognition — self-awareness in Descartes’ case, knowing right from wrong per St. Augustine —…
Several species of bacteria and fungi were found living in the central nervous system (CNS) of patients with amyotrophic lateral sclerosis (ALS) that could potentially be related to the development of the disease, a study reports. However, according to the researchers, more studies are still needed to confirm if…
Stepping Out of My ‘ALS Silo’
Growing up in Iowa, I knew that silos were beneficial for farmers who used them to store grain and corn. When I entered the workforce, silos were a negative thing. It was a term used to describe how some departments or managers don’t share information with other departments…
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