The U.S. Food and Drug Administration (FDA) has given the green light to Biohaven Pharmaceuticals to advance sublingual BHV-0223, which regulates glutamate communication between neurons, into clinical trials for amyotrophic lateral sclerosis (ALS) patients. The FDA’s permission to go ahead with the study followed Biohaven’s submission of an investigational new drug…
FDA OKs Biohaven’s Sublingual BHV-0223 for Clinical Investigation
Repeated severe trauma to the body or mild injuries to the head — especially at midlife — raise a person’s risk of ALS, a European case-control study from the EURALS consortium shows. The new research, “Trauma and amyotrophic lateral sclerosis: a european population-based case-control study from…
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An ALS Documentary: ‘Mr. Connolly Has ALS’
https://vimeo.com/216244227 This film by Dan Habib is all about the extraordinary life of high school principal Gene Connolly. Connolly was the much-loved principal of Concord High School for 14 years before he was struck by amyotrophic lateral sclerosis (ALS) in 2014. MORE: Explaining the progression…
Children’s National Health System no longer treats just kids. Its Rare Disease Institute, launched in April 2017, has partnered with the National Organization for Rare Disorders (NORD) to become the first of many U.S. “centers of excellence” to look after patients with rare diseases, regardless of age. The effort…
In some neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), nerve cells fold their proteins incorrectly, leading to cell death. Using plants, researchers discovered that when defective proteins accumulate in chloroplasts – a plant’s cellular compartment where photosynthesis occurs – it generates a distress signal that produces reparative proteins to…
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Motor Neurons’ Role in ALS
In this short film from Project ALS (a research-based non-profit organization founded by Jenifer Estes), the role motor neurons play in amyotrophic lateral sclerosis (ALS) is discussed. MORE: Study validates the use of social cognitive measure in ALS patients The computer-generated graphics explains what happens when…
A nervous system mechanism that helps control heart rate and blood pressure goes into overdrive in patients with a type of ALS that eliminates mobility and sensation in some limbs, a study reports. The control mechanism is known as sympathetic vascular response — with vascular response referring to heart blood vessels.
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Lessons Learned from Echo Show
Recently, thanks to my ALS News Today publisher, I had the exciting opportunity to test out an Echo Show. Why would I rate that as exciting? Well, we already owned an Amazon Echo (tower-type) device, but with my ALS-affected voice, I was batting zero activating it.
BrainStorm Cell Therapeutics is expanding the patent portfolio that protects its NurOwn technology for the treatment of several diseases affecting the central nervous system. The latest U.S. patent claim includes Parkinson’s disease and ALS (amyotrophic lateral sclerosis). The announcement by BrainStorm follows a Notice of Allowance issued by…
Amyotrophic lateral sclerosis (ALS) is a disease that progressively shuts down your muscles by attacking certain cells in the brain and spinal cord that are needed to keep muscles moving. Eventually, patients will lose their mobility, have trouble moving, walking, swallowing and even breathing. MORE: 13 facts about ALS…
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