Gene activity altered in certain brain cells of people with C9-ALS

Gene activity altered in certain brain cells of people with C9-ALS

The genetic activity of certain brain cells, namely excitatory neurons and astrocytes, is altered in people with amyotrophic lateral sclerosis (ALS) caused by mutations in the C9ORF72 gene, a study reports. The data reveal the distinct molecular mechanisms that may lead to disease progression in people with such mutations, which…

ALS Is My Next Mountain to Climb

This content is sponsored by Mitsubishi Tanabe Pharma America, Inc. (MTPA) and is intended for U.S. audiences only. Any other present or future content posted by the contributor, not expressly designated as “Mitsubishi Tanabe Pharma America, Inc.-sponsored content” is not associated with MTPA. Albert is an actual patient who is…

How hope is everywhere when our community gathers

This past Sunday dawned crisp and cool on the eastern shore of Maryland, with a hint of light rain falling from a few clouds dappled against an otherwise vivid blue sky. I dressed to be outdoors, making sure my orange Tim Lowrey Panel T-shirt was visible under my jacket,…

Man with ALS controls devices using brain-computer interface

A man with amyotrophic lateral sclerosis (ALS) was able to control external devices — lighting and a TV — with only his thoughts using a brain-computer interface (BCI) device, according to a recent study. Called Cortical Communication (CortiCom), the BCI system learns to predict a person’s intended action by…