ALS News Today brought you daily coverage of important discoveries, treatment developments, clinical trials, and other events dealing with amyotrophic lateral sclerosis (ALS) throughout 2018. As a reminder of what mattered most to you in 2018, here are the 10 most-read articles of last year with a brief description…
A new, more targeted rat model of swallowing problems may lead to better understanding of ways to preserve and even restore tongue function in patients with amoytrophic lateral sclerosis (ALS), according to a study. The study, “Hypoglossal Motor Neuron Death Via Intralingual CTB-saporin (CTB-SAP) Injections Mimic…
Exploratory analysis of data collected in the FORTITUDE-ALS and VITALITY-ALS trials sponsored by Cytokinetics provide new insights to enhance the design of future clinical trials in amyotrophic lateral sclerosis (ALS). These findings were discussed at the 29th International Symposium on ALS/MND in Glasgow, Scotland, in several poster…
Sexuality and intimacy are important aspects of one’s life that are also affected by amyotrophic lateral sclerosis (ALS), according to a review study. It is important that clinicians and healthcare practitioners provide suitable support to ALS patients to cover these issues, as they can also affect patients’ overall well-being and…
Biogen has decided to exercise its option to acquire from Ionis Pharmaceuticals the exclusive rights to develop and commercialize BIIB067 as a potential treatment for amyotrophic lateral sclerosis (ALS). The decision to license the investigational therapy is covered under the terms of a collaborative agreement between the two companies…
A natural compound found in certain fruits and vegetables, called resveratrol, may help boost the ability of mesenchymal stem cells taken from amyotrophic lateral sclerosis (ALS) patients to transform into mature nerve cells, researchers in Korea report. This finding, detailed in a study published in the Journal of Tissue…
Cytokinetics has completed patient enrollment in its Phase 2 trial to evaluate the safety and potential of reldesemtiv to improve muscle function in patients with amyotrophic lateral sclerosis (ALS), the company announced. The trial (NCT03160898), called FORTITUDE-ALS, includes about 450 ALS patients in the U.S., Canada, Europe,…
Amyotrophic lateral sclerosis (ALS) is a progressive neurological condition that affects motor neurons. Motor neurons are nerve cells that control the movement of voluntary muscles, including respiratory muscles. Respiratory failure is the most common cause of death in ALS patients. Lung function tests are used to assess the risk…
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease, and inheritance is thought to play an essential role in its less common form, called familial ALS (FALS). A genetic test is usually only performed on individuals with a known family history of ALS. Familial versus sporadic ALS The…
NSI-566 is an experimental stem cell-based therapy that Seneca Biopharma (previously known as Neuralstem)Â is developing as a potential treatment for amyotrophic lateral sclerosis (ALS). The company also is investigating NSI-566 as a potential treatment for chronic spinal cord injury and to restore motor deficits…
