Heavy metal pollution may not be as important as previously thought in the development of amyotrophic lateral sclerosis (ALS), according to new research by Italian scientists.

Researchers from the U.S. found a way to allow small substances to cross the blood-brain barrier and reach areas of the brain that are normally inaccessible. This means that drugs that are developed for the treatment of neurological conditions such as amyotrophic lateral sclerosis (ALS) could reach the brain and exert their activity.

Long-term use of Rilutek (riluzole) is associated with a better outcome in sporadic amyotrophic lateral sclerosis (ALS) patients, whereas short-term use seems to have little effect on survival according to a study published in the scientific journal Frontiers in Aging Neuroscience.

Insmed has launched a first-in-human clinical trial evaluating its experimental gene therapy INS1202 in people with amyotrophic lateral sclerosis (ALS). The Phase 1 study, called ARMOR (NCT07290062), aims to enroll about 23 adults with ALS, ages 18 to 80, who have been living with the disease for…

An experimental nerve-protecting therapy called RT1999 (smilagenin) will soon be tested in people with amyotrophic lateral sclerosis (ALS) as part of a U.K. platform trial designed to quickly screen potential ALS treatments. The study, called EXPERTS-ALS, is testing several experimental ALS therapies…

Chris was diagnosed with ALS in 2024. Before that, he spent 40 years in the oil and gas industry, working and living in eight countries across five continents. He’s dedicated himself to helping others with ALS move forward. This content is sponsored by Tanabe Pharma America, Inc. (TPA) and is…

A specific alteration in the TDP-43 protein can reduce the viability of nerve cells in a lab model of amyotrophic lateral sclerosis (ALS), causing problems with energy generation and molecular transport within the cell, a new study finds. Notably, however, researchers found that this mutation does not cause TDP-43 protein…

This content is sponsored by Tanabe Pharma America, Inc. (TPA) and is intended for US audiences only. Any other present or future content posted by the contributor, not expressly designated as “Tanabe Pharma America, Inc. – sponsored content” is not associated with TPA. The information provided here is general in…

Ed and his wife Karen were shocked to hear his ALS diagnosis, but with the help of the VA and others in their community, they discovered they were far from alone. This content is sponsored by Tanabe Pharma America, Inc. (TPA) and is intended for US audiences only. Any other…

This content is sponsored by Tanabe Pharma America, Inc. (TPA) and is intended for US audiences only. Any other present or future content posted by the contributor, not expressly designated as “Tanabe Pharma America, Inc. – sponsored content” is not associated with TPA. The information provided here is general…