Oregon State University researchers were able to stop the progression of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) for nearly two years in a specific type of mouse model. The treatment allowed the animals to live for 650 days – 500 days longer than any other previous treatment has managed.

Researchers at Columbia University, New York recently published in the journal Cell Reports their findings on eight different master regulators involved in amyotrophic lateral sclerosis (ALS) neurodegeneration in mouse models. The study is entitled “The Regulatory Machinery of Neurodegeneration in In Vitro Models…

The ALS (amyotrophic lateral sclerosis) Association revealed that a team of researchers funded by the Association and led by Dr. Timothy Miller and Dr. Randall Bateman from Washington University in Saint Louis, recently discovered important insights into the ALS-related protein called copper (Cu)/zinc (Zn) superoxide dismutase (SOD1). ALS…

A research team from Pitié–Salpêtrière Hospital in Paris found major structural alterations of the neuromuscular junctions (NMJs) in early stage Amyotrophic Lateral Sclerosis (ALS) patients. The study entitled “Endplate denervation correlates with Nogo-A muscle expression in amyotrophic lateral sclerosis patients” was published April 2015 in…

Researchers at Johns Hopkins University recently published in the journal PLOS ONE a novel resource to aid in studies focused on amyotrophic lateral sclerosis (ALS) pathogenesis and related drug development. The study is entitled “A Comprehensive Library of Familial Human Amyotrophic Lateral Sclerosis…