Denali and Sanofi Partner to Advance Small Molecules That Might Treat ALS, Other Diseases
Denali Therapeutics and Sanofi have joined efforts to develop small molecule inhibitors of the RIPK1 enzyme, a new…
Articles by Alice Melão
SOD1 Variants Can Have Different Effects on Nerve Cell Populations, Study in Worms Reveals
SOD1 gene mutations can contribute differently to the degenerative process of nerve cells involved in the progression of amyotrophic…
Health Canada Authorizes Radicava for Treatment of ALS
Canadian authorities have approved the sale of Radicava (edaravone) to treat patients with amyotrophic lateral sclerosis (ALS). The therapy will…
FDA Gives OK to Medicinova’s Phase 3 Clinical Trial Plan for Ibudilast in ALS
The U.S. Food and Drug Administration has given positive feedback to MediciNova’s Phase 3 developmental plan for its investigational…
ALS, Frontotemporal Dementia Have Distinct Patterns of Brain Inflammation, Study Shows
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are caused by different patterns of inflammation in the brain, which…
Problems with Behavior and Thinking Skills Evident in ALS Patients and Progress with Disease, UK Study Says
Amyotrophic lateral sclerosis’ toll on the thinking abilities and behavior of patients is as progressive and damaging as the disease’s physical…
Challenges, Benefits of Noninvasive Mechanical Ventilation for ALS Patients Reviewed in Study
Survival and quality of life of patients with more advanced amyotrophic lateral sclerosis (ALS) can be improved significantly with…
Poorer Ability to Regulate Body Temperature May Be ALS Symptom, Mouse Study Suggests
A diminished ability to regulate body temperature may be a manifestation of amyotrophic lateral sclerosis (ALS), results of a mice…
CannTrust Partnering with Australian Hospital for Trial Testing Cannabidiol Capsules for ALS
CannTrust is getting ready to launch a clinical trial to assess the effectiveness of its cannabidiol (CBD) oil…
Gene Level Profiles in ALS Are Informative, but Lack Diagnostic Value, Study Finds
Determining genetic profiles from patients’ blood samples can provide a broad view of the biological processes involved in amyotrophic…