ALS Patients Commonly Use Complementary and Alternative Medicines, Review Study Reports
Despite a lack of clinical evidence, complementary and alternative medicines (CAM) are often used by patients with amyotrophic lateral…
Articles by José Lopes, PhD
mRNA Linked to ALS and Other Disorders Found at High Levels in Nerve Fibers, Study Reports
RNA molecules that are associated with genetic disorders characterized by damage to nerve fibers are found at higher-than-usual numbers in…
Psychological Stress Not a Risk Factor for ALS, Study Suggests
Psychological stress does not appear to play a part in the development of amyotrophic lateral sclerosis (ALS), with patients showing…
BioElectron’s EPI-589 Shows Positive Results in ALS Patients in Phase 2a Trial
Investigational compound EPI-589 was found to be safe and well-tolerated, improved biomarkers of neuroinflammation, and showed signs of slowing…
Misfolded SOD1 Protein May Have Key Role in Sporadic ALS, Study Suggests
Specific patterns of a misfolded protein — superoxide dismutase 1 (SOD1) — are found in the brain and spinal cord of…
Protein Staufen1 Could Be Target for Future ALS Therapies, Mouse Study Suggests
Depleting a protein called Staufen1 improved motor function and lowered protein aggregation in a mouse model of spinocerebellar ataxia…
FDA Approves Tiglutik, Liquid Form of Riluzole, for ALS Patients
The U.S. Food and Drug Administration (FDA) has approved Tiglutik, an oral suspension of riluzole, for the treatment of…
Both Spinal and IV Infusions of Stem Cells Safe for ALS Patients, Phase 1 Trials Report
Stem cell transplants given to amyotrophic lateral sclerosis (ALS) patients were safe and feasible whether infused intravenously or via…
Reduced Tightening of Pharynx Underlies Impaired Swallowing in ALS Patients, Study Reports
Impaired tightening of the pharynx is associated with inefficient swallowing in patients with amyotrophic lateral sclerosis (ALS), according to…
Physicians Asked to Help ALS Patients Die Must Evaluate Motivations, Alternatives, Case Report Says
Physicians who help amyotrophic lateral sclerosis (ALS) patients die should carefully evaluate their motivations, capacity, and care goals, while also discussing…