• This topic is empty.
Viewing 0 reply threads
  • Author
    Posts
    • #21724

      A few years ago there was a phase II of Guanabenz in Italy. Guanabenz is a drug used to treat hypertension.
      The results indicated that this drug was roughly as effective as AMX0035 from Amylyx.
      Yet at the dose tested, this drug was unsafe on the long term so a new version was designed: Sephin 1.
      This new drug will be tested in a few months in France and Italy in a new phase II trial.

      InFlectis’ IFB-088 Earns Orphan Drug Status

      I guess the mecanism of this drug and of sodium phenylbutyrate is interesting as they both address the cellular stress even if an opposite way.
      My understanding is that after the failure of Arimoclomol, and the two genetic therapies (SOD1 and C9orf72) of Biogen, research should study new paradigms. Cellular stress in ALS and other neurodegenerative diseases offers a clear mechanism of action when most proposed drugs fail to do so.

Viewing 0 reply threads
  • You must be logged in to reply to this topic.

©2022 KLEO Template a premium and multipurpose theme from Seventh Queen

CONTACT US

We're not around right now. But you can send us an email and we'll get back to you, asap.

Sending

Log in with your credentials

or    

Forgot your details?

Create Account

Verify you are not a robot