Flex Pharma has begun a Phase 2 clinical trial assessing FLX-787 in patients with amyotrophic lateral sclerosis (ALS). The aim of the study, taking place in Australia, is to evaluate the safety and efficacy of FLX-787 in treating ALS-related leg cramps and/or spasticity. Patients with ALS — a…
Phase 2 Study of Treatment for ALS-Induced Cramps, FLX-787, Underway in Australia
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Stress Relievers for ALS
Relieve Stress the Easy Way How do you relax? Relaxing the mind could be the most difficult thing to do. Has anyone ever told you to “just relax?” There’s something about those words — relax, be calm, and calm down — that trigger a deep emotional response in most of…
Caregivers play an important role in the treatment and support of people with amyotrophic lateral sclerosis (ALS), although that role is not always appreciated or regarded by researchers. A recent study focused on the impact of caregiving on those who take care of people with ALS, highlighting how the disease affects both patients and those…
Although cognitive impairment is common in patients with ALS, the reliability of the “Reading the Mind in the Eyes Test” (RMET), a measure of social cognitive function, had yet to been established. Here, researchers confirm this is a reliable and efficient measure of social cognition in amyotrophic lateral sclerosis (ALS) patients,…
Magnetic resonance imaging (MRI) techniques may detect biomarkers for early diagnosis in patients with amyotrophic lateral sclerosis (ALS), according to a review study titled “The value of magnetic resonance imaging as a biomarker for amyotrophic lateral sclerosis: a systematic review,” published in BMC Neurology. Biomarkers are measurable substances, such…
Patients with amyotrophic lateral sclerosis (ALS) may have problems recognizing emotions in other people, even though they do not have other cognitive or behavioral problems. This inability is linked to microscopic changes in brain anatomy in regions linked to emotional processing, and resembles changes seen in patients with some types of…
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ALS Quote by Stephen Hawking
Stephen Hawking Quote about ALS Stephen Hawking is likely the most well-known theoretical physicist. He is also likely the most well-known person living with ALS. Hawking has a rare slow-progressing form of ALS that has gradually left him paralyzed. He communicates using a single cheek muscle attached to a…
A new study led by researchers with the United Nations (UN) has projected that the number of cases of amyotrophic lateral sclerosis (ALS) will increase by 69% over the next 25 years, primarily due to population ageing. According to the study “Projected increase in amyotrophic lateral sclerosis…
Astroglial cells in the brain were seen to contribute to the death of neurons by promoting inflammation in an in vitro laboratory model of sporadic amyotrophic lateral sclerosis (ALS). Astrocytes are brain cells that are usually known for their protective role toward neurons in conditions such as stroke and spinal cord injury. But…
The U.S. U.S. Food and Drug Administration (FDA) has accepted Mitsubishi Tanabe Pharma’s new drug application (NDA) for edaravone as a treatment for amyotrophic lateral sclerosis (ALS). A decision regarding the intravenous treatment is expected by June 16, 2017, based on the U.S. Prescription Drug User Fee Act. If it is…
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