Mutations in the TDP-43 gene might not be causing the disease changes seen in amyotrophic lateral sclerosis (ALS) on their own, but might need additional environmental or genetic factors to trigger disease. This was the conclusion of scientists at the Oregon Health & Science University who studied mutant forms…
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Ipsen Biopharmaceuticals has entered an exclusive three-year agreement with Saol Therapeutics to promote Dysport (abobotulinumtoxinA), a therapy indicated for injection in adults with spasticity and in children with lower limb spasticity – common in amyotrophic lateral sclerosis (ALS) patients. Under the agreement, Saol will set up a…
Worldwide Clinical Trials was selected as the Clinical Research Organization (CRO) to run a Phase 3 study of the investigational stem-cell therapy NurOwn for the treatment of amyotrophic lateral sclerosis (ALS). BrainStorm Cell Therapeutics, which developed NurOwn, expects the collaboration will provide all of the necessary requirements to pursue the placebo-controlled,…
Mitsubishi Tanabe Pharma America (MT Pharma America) has enrolled more than 700 sites of care in its newly created National Infusion Center Directory to help physicians identify local infusion centers for amyotrophic lateral sclerosis (ALS) patients who are prescribed Radicava (edaravone).
Amyotrophic lateral sclerosis (ALS) is a progressive muscle-wasting condition. Although it can affect each patient in different ways, as the condition worsens many may find it increasingly difficult to eat and drink. Common issues can include difficulties chewing and swallowing as the muscles of the throat and mouth weaken. The…
H.P. Acthar Gel (repository corticotropin injection) is an investigational treatment for amyotrophic lateral sclerosis (ALS) being developed by Mallinckrodt Pharmaceuticals. It is administered as an injection. The drug is currently approved to treat various other conditions, including multiple sclerosis (MS). How H.P. Acthar Gel works ALS is a…
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder. In ALS patients, the gradual death of nerve cells in the brain and spinal cord that control muscles can result in weakened muscles throughout the body. As the disease progresses and more muscles are affected, getting around and accomplishing…
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder. In patients with ALS the gradual death of nerve cells in the brain and spinal cord that control muscles can result in the progressive weakening of muscles throughout the body. The severity of symptoms experienced by patients with ALS can change…
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which the gradual death of nerve cells in the brain results in a progressive weakening of muscles throughout the body. While the symptoms of ALS often vary among patients, breathing problems will at some point confront all of them. When the muscles involved in breathing weaken,…
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An ALS Documentary: ‘Mr Connolly Has ALS’
https://vimeo.com/216244227 This film by Dan Habib is all about the extraordinary life of high school principal Gene Connolly. Connolly was the much-loved principal of Concord High School for 14 years before he was struck by amyotrophic lateral sclerosis (ALS) in 2014. MORE: Explaining the progression…