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March 9, 2021 News by Steve Bryson, PhD

Shrinkage in Cell Structures Occurs in Early Disease Stages

Changes to a critical structure within the cell nucleus of spinal nerve cells — the nucleolus — preceded the appearance of other disease markers in people with either familial or sporadic forms of amyotrophic lateral sclerosis (ALS), a study has discovered. …

December 1, 2020 News by Aisha I Abdullah PhD

Polio-related Research Into Brain Motor Network Shows Potential ALS Marker

New research into the motor networks of polio survivors shows the brain may “rewire” itself in neurological diseases, leading to a reorganization that also may serve as a potential biomarker of amyotrophic lateral sclerosis (ALS) and other motor neuron disorders, a study reports.  Published in…

July 18, 2019 News by Ana Pena, PhD

Specific Nerve and Other Cells in Spine Unique to ALS Patients and May Be Early Markers of Disease, Study Says

Specific populations of neurons and associated cells in the spinal cord of people with sporadic amyotrophic lateral sclerosis (ALS) may serve as early biomarkers for the disease, a study has found. The newly discovered populations offer scientists a chance to learn more about the first steps underlying ALS and…

July 1, 2019 News by José Lopes, PhD

Helping Motor Neurons in Spinal Cord Break Down Toxic Proteins as Well as Other Cells Do May Treat ALS, Study Finds

Differences in how efficiently nerve cells degrade and discard proteins may explain why some motor neurons better resist a buildup of toxic proteins than do others in people with amyotrophic lateral sclerosis (ALS), according to a study in mice. The study, “Stem cell-derived cranial and spinal motor…

March 28, 2018 News by Catarina Silva

Tiny Brain Blood Vessels Stimulate Movement Nerve Cell Growth, Study Reports

The brain’s smallest blood vessels stimulate the growth of spinal cord nerve cells at an early stage of their development, researchers at Southern California’s Cedars-Sinai group report. Their discovery, made with a tiny biological chip, could help shed light on the causes of amyotrophic lateral sclerosis (ALS). The article they wrote…

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