Enrollment Completed for Phase 3 REFALS Trial Evaluating Levosimendan in ALS Patients
The Phase 3 REFALS trial exploring the impact of oral levosimendan (ODM-109) in patients with amyotrophic lateral sclerosis (ALS)…
Articles by Alice Melão
Multidisciplinary Care Linked to Increased Survival, Spanish Study Shows
Multidisciplinary care with timely use of respiratory and feeding support contributes to increased survival for people with amyotrophic lateral…
Vitamin D Supplements Cannot Prevent Motor Function Decline in ALS Patients, Study Suggests
Vitamin D supplementation can help overcome low levels of the vitamin often detected in people with amyotrophic lateral sclerosis (ALS).
MediciNova Launches Phase 2b/3 Trial of Ibudilast for ALS
MediciNova has launched the Phase 2b/3 clinical trial that will explore the potential of ibudilast (MN-166) in…
Electronic App to Monitor Dietary Intake May Benefit ALS Patients, Trial Data Suggest
A diet monitoring app can help amyotrophic lateral sclerosis (ALS) patients to manage their calorie intake in order to maintain…
FDA Approves Pivotal Phase 2b/3 Trial for Ibudilast in ALS Patients
The U.S. Food and Drug Administration approved MediciNova’s plans for a pivotal Phase 2b/3 clinical trial that will explore…
Improving Oxygen Supply to the Spinal Cord May Help Prevent ALS Progression, Mouse Study Suggests
Increasing blood flow in the spinal cord by injecting a long-acting vasodilator can help prevent the progression of amyotrophic lateral…
Zebrafish May Be Useful Experimental Model to Study ALS Associated with Angiogenin Mutations, Study Shows
Widely used to study several human diseases, zebrafish can now be a useful preclinical model to study amyotrophic lateral sclerosis…
Stem Cell Therapy Can Improve Survival, Motor Function of Mice with SOD1 Mutation, Study Shows
Stem cell therapy using a certain type of stem cell called human mesenchymal stromal cells (hMSCs) may have the potential…
Newly Identified GLT8D1 Genetic Variants Linked to Familial ALS, Study Reveals
New genetic mutations in the coding sequence of the GLT8D1 enzyme have been identified and linked to inherited amyotrophic…