Spanish Researchers Find New Link Between TDP-43 Protein and Autophagy in ALS
A recent study highlights a previously unknown function of the TDP-43 protein in nerve cells that may contribute to the…
Articles by Alice Melão
AcuraStem Awarded $3.7M to Develop Gene-related Therapy for ALS, Frontotemporal Dementia
The National Institute of Neurological Disorders and Stroke (NINDS) awarded $3.7 million to AcuraStem to support the development of…
Kentucky Study Looking to Treat Genetic Form of ALS with Clusters in Appalachia
A university-led clinical trial will assess the therapeutic effect of Celestone (betamethasone) injections in amyotrophic lateral sclerosis (ALS) patients…
Changes in Brain Structure, Blood Flow Linked to Varying Cognitive Deficits in ALS
Cognitive deficits associated with amyotrophic lateral sclerosis (ALS) are linked to a particular pattern of abnormal changes and altered blood…
Infusing Treg Immune Cells Has Potential to Slow ALS, Small Study Suggests
Results from a Phase 1 clinical trial reveal that giving patients infusions of a specialized immune cell may be a…
Two Enzymes Play Key Role Against Stress Granules in ALS, Other Neurological Disorders, Study Finds
Two enzymes called USP5 and USP13 were found to have an important role in fighting back against toxic “stress…
New Mouse Model Reveals Process Involved in Neuroinflammation in ALS, Other Disorders
A new mouse model developed by researchers at Karolinska Institute in Sweden revealed a molecular mechanism that may contribute…
Protein That Helps to Regulate Innate Immune System Seen to Slow ALS Progression in Early Study in Mice
The protein TRIF can prevent resident immune cells of the brain from activating abnormally and slow the progression of amyotrophic lateral…
MIT Researchers Find Potential Role of C9orf72 Gene in ALS, Frontotemporal Dementia
Mutations in the C9orf72 gene deregulate the process by which cells remove waste, leading to a buildup of toxic…
#AAN2018 — NurOwn’s Beneficial Effect in ALS Sustained by miRNA Regulation, Study Suggests
NurOwn, a cell therapy being developed by Brainstorm Cell Therapeutics, is able to maintain its therapeutic effects by significantly regulating the…