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December 8, 2020 at 6:34 pm #17065Dagmar MunnKeymaster
Many ALS patients are interested in the role of diet in the management of ALS, asking: Is there a special diet to follow? Or: Does it even matter at all?
This interesting webinar by Dr. Richard Bedlack presents recent work linking the gut microbiome and ALS. Tell us your thoughts on this topic.
Is the Key to Stopping ALS Being Flushed Down Our Toilets?
Richard Bedlack, MD, PhD, Duke ALS Clinic and Katharine Nicholson, MD, Sean M. Healey & AMG Center for ALS at MGH
The gut microbiome is the family of organisms that live inside our GI tracts. It is very clear that the gut microbiome plays a role in gastrointestinal diseases. Recently, evidence is emerging that the gut microbiome may play a role in driving ALS progression. Here we will review the microbiome, its role in gastrointestinal diseases, and the recent work linking it to ALS. We will highlight the next steps being taken to better understand whether and how manipulation of the microbiome might be undertaken to slow, stop or reverse ALS progression.
What do you think?
December 14, 2020 at 3:12 pm #17172Jean-Pierre Le RouzicParticipant
I did not check the video but there is a funny story about mouse poop at Alzforum.
To simplify an ALS mice model at Harvard get ill while the same animal model is healthy in MIT or Jackson labs.
The reason? If we listen the scientists, it is perhaps because mice’s gut microbiome is different at Harvard.
However mice are notoriously extremely sensitive to their carers, a mouse that feels it is loved is usually healthier.
If instead you want to be very serious, look at Braak stages for Alzheimer and Parkinson. It may apply as well to ALS but it was never seriously investigated. Oddly it’s an old stuff … 2003, that seems to have been rediscovered recently.
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