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Genetic Mutations and Muscle cramps?
pALS with a known genetic mutation, did you have symptoms at an very early age that in retrospect you wonder if they were related all along to the genetic mutation or the onset of ALS? My father and grandfather both had extreme cramps in their calves and hamstrings. They also both had severe toe curling cramps. My father asked me if I experienced these and I said yes starting in my teens. He also said he remembered the toe curling cramps starting when he was young. When I asked the doctor for the pre-fALS study about this he said that was part of what they were looking into.
Did you experience anything unusual in your muscles or body? What genetic mutation do you have? Do other family members with the mutation have similar experiences?
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