ALS News Today Forums Forums Living With ALS Gabapentin, good or bad for ALS?

  • Gabapentin, good or bad for ALS?

    Posted by bob-scannell on March 25, 2021 at 8:12 am

    My wife, who has ALS, was having severe itching issues. We tried various things, then a doc suggested Gabapentin.  So far it seems to have helped the itching.  I have also read that there are some potential other positives about Gabapentin for ALS, which is encouraging to maybe stay on this med.  But, I have also read some potential downsides, including I think added weakness, etc.   Does anyone have long term experience with Gabapentin for ALS?

    jim-conner replied 2 years, 5 months ago 7 Members · 6 Replies
  • 6 Replies
  • jesus4life

    March 25, 2021 at 8:50 pm

    I too am curious what other ALS patients have experienced with this. My ALS doctor just prescribed Gabapentin (100 mg at night) to help with possible sciatica (low back) pain & leg pain & swelling. I’m also taking Baclofen for muscle cramping.

  • carolyn-barry

    March 26, 2021 at 7:45 am

    I’ve been taking 400mg of Gabapentin since October.  My neurologist prescribed it specifically for the pain in my feet, which is not only caused by my ALS but the peripheral neuropathy in my feet is also a factor.  The pains had gotten severe enough to wake me up several times during the night.  I haven’t had any side effects whatsoever from the drug, and while it has stopped the waking at night, it hasn’t completely eliminated the daytime pain.  It has not caused any increased weakness in my walking.  I had previously tried Duloxetine and then Nortryptilene, but had to discontinue both because I they each caused a negative effect on my bladder function.  I plan on continuing the Gabapentin, because overall my pain has lessened.

  • chuck-russell

    March 26, 2021 at 8:58 am

    I have besn on gabapentin 300 mg, 3 times a day, for about 18 months. Mine is also for neuropathy in my feet. I was diagnosed with ALS about 26 months ago. I can’t say anything about increased weakness, I’ve been on it for awhile, I still get around. Of coarse I have weaken, I mean thats the nature of this challange but, I don’t think it has increased because of the gamapentin. I do know this, if I don’t take it, my feet really really don’t like me.

  • lowell

    March 27, 2021 at 10:57 pm

    I also was diagnosed 24 months ago. I have been taking it for 24 months, 600mg 3 times a day for my knee. If I don’t take it my knee will sometimes just buckle. However I think that is due to another injury that has nothing to do with my als. I don’t notice any issues concerning weakness.

  • gideon

    March 30, 2021 at 11:03 pm

    My wife taking Gabapentin 300mg x3 three  time a day for about two years.

    I try to reduce Gabapentin by 1/3, The consequence was my wife hands start shaking ,

    went back to original dose.

    P S if you taking pill for depressing ,  Do not taking it with Gabapentin


  • jim-conner

    April 29, 2021 at 12:00 pm

    Gabbies? I tried it for 1 year for pain before my ALs diagnosis. Did nothing at all. My neurologist took me off when I was diagnosed. My daughter is an Addiction Counselor. She told me Gabbies are used in combination with certain drugs to accelerate the “high”.  Keep them away from prying eyes.

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