Amyotrophic lateral sclerosis (ALS) is commonly referred to as Lou Gehrig’s disease. But who was Lou Gehrig? Henry Louis Gehrig was born in New York on June 19, 1903, at a time when very few people were aware of ALS, the progressive and neurodegenerative disease. Gehrig grew up to…
Who Was Lou Gehrig?
Seize the Day! Lately that’s been my morning mental mantra. I visualize it as a chant and it’s the secret weapon I use every December to help me adjust to the onset of winter and face the end of the year. Even though I’m lucky to live…
BrainStorm Cell Therapeutics released new data on potential biomarkers from its Phase 2 trial investigating NurOwn, the company’s cell therapy for amyotrophic lateral sclerosis (ALS), at the International Symposium on ALS/MND meeting held in Boston last week. Both these findings and an ongoing Phase 3 trial, now recruiting patients in…
Pivotal Phase 3 clinical trial results presented at this year’s 28th International Symposium on ALS/MND reveal that Cytokinetics‘ investigational therapy tirasemtiv failed to provide a positive therapeutic impact on both muscle strength and slow vital capacity (SVC) in ALS patients. The results, which were presented by Jeremy Shefner, MD,…
The rate of ALS patients’ lung-function decline can predict their risk of breathing failure, their need for assisted ventilation, and their risk of death, according to Cytokinetics, a company that develops muscle-disease therapies. “These results suggest that respiratory function is an important prognostic indicator of clinical progression in people with…
Additional data on Radicava (edaravone) and the clinical trial that led to its approval to treat amyotrophic lateral sclerosis (ALS) will be presented in oral and poster presentations at the 28th International Symposium on ALS/MND that opens in Boston on Friday. Mitsubishi Tanabe Pharma America announced that its one oral…
7 Things to Keep in Mind If a Loved One Has ALS
An amyotrophic lateral sclerosis (ALS) diagnosis can be devastating for both the patient and their family. If a loved one has recently been diagnosed with ALS, they’ll need your support now more than ever. Remember to be understanding and patient. We’ve put together a list of things to consider if a someone close to you has…
Understanding Molecular Changes in ALS
In this TEDx Talks video, Steven Boeynaems explains that although we have known about amyotrophic lateral sclerosis (ALS) for 140 years, scientists still know very little about the condition that affects around 200,000 people worldwide. MORE: Seven interesting facts about ALS Boeynaems talks about the role of TDP-43 proteins and…
Using stem cell treatments to protect motor neurons is not enough to prevent the loss of nerve-muscle connections and disease progression in a mouse model of amyotrophic lateral sclerosis (ALS), researchers from Italy found. The study, published in the journal Stem Cell Research, had exposed mice to repeated brain…
Takeda Canada and the Montreal Neurological Institute (MNI) are teaming up to conduct joint research aimed at developing new therapies for amyotrophic lateral sclerosis (ALS). The collaborative effort includes developing and examining multiple cell assays from ALS patients over the next three years, from 2017 to 2020,…
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